SawtoothWolf I'm baffled these so-called directors and script writers even got funding for this garbage. There are so many people out there with talent who do much more with a fractional amount of money to spend. This flick has no qualities whatsoever. The story is lame, predictable, and overall hilarious. The acting is emotionless and atrocious. To sum it up - this is, without a doubt, far and away the worst film I have ever tried to sit through. Everything about is annoying, dumb, and forgettable. I believe I can differ between a movie which simply isn't my cup of tea, and one that's just utterly bad. This one definitely belongs into the second category.

Jenalena Sinclair This movie was the biggest waste of time ever !! Not only was the plot and script CRAP the actors were very terrible too!!! I expected so much more from Alyssa Milano. The corny come up with the "good doctor" gone bad is just stupid. Why would he not like Jack at first if in the end he was just gonna buddy up with him. Now I like horror and thriller and crime movie but this was unacceptable. There was no motive, no concept... Just a cheap budget film with amateur sex scenes and gore. I would have rather watched Saw. I expected so much more of this movie and it could have been better if they had a different director and script. This movie had so much potential and I'm so disappointed how it turned out. IF YOU CAN AVOID THIS MOVIE PLEASE DO BECAUSE IT WILL BLOW YOUR BRAINS HOW STUPID IT IS!!!!

John-The-Roman I expected quite a bit coming from the makers of Crank, but left this film sorely disappointed. Though it yields an interesting plot, there are several cliché scenes stitched together meant to be disturbing, which are actually quite comedic. A very typical plot twist ending left a lot to be desired. Some pretty good gore scenes, but not enough to carry the film as a top-notch gorefest to at least make up for its dry acting, and laughable sex/death/violence scenes. Though the medical terms and science behind it is quite good, it is not enough to save this movie from being just another stereotypical, modern-day teenage horror film. Good enough for a one time watch, but that's about all.

ironfist699 This is a movie that everyone should see..or no one..and why is that? its disturbing shocking annoying its making you think of things that you never have,a dark side of human nature,the story is great actors great direction great twists unique dialogues ausome.after seeing a lot and i mean a lot of movies of this kind i can insure you that this one is excellent,surprising brilliant i do not understand why people here do not get it,or maybe i do they have absolutely no clue about cinema thats why. this one will carry you away to your darkest deeper most hidden thoughts,it will give you another prospective of every day life. a prospective society made us forget.a movie for smart people made by smart people.